PULM

Pulmonary

Fact 2 of 2

Obstructive vs Restrictive Lung Disease

Obstructive = difficulty exhaling (↓FEV1/FVC), Restrictive = difficulty inhaling (normal or ↑FEV1/FVC with ↓total volumes).

Detailed Explanation

Obstructive Lung Diseases:

  • COPD (emphysema, chronic bronchitis)
  • Asthma
  • Bronchiectasis
  • Spirometry Pattern:

  • ↓ FEV1
  • ↓ or normal FVC
  • ↓ FEV1/FVC ratio (<70% or <0.7)
  • ↑ TLC, ↑ RV (air trapping)
  • Restrictive Lung Diseases:

  • Pulmonary fibrosis (IPF)
  • Pneumoconioses
  • Sarcoidosis
  • Chest wall disorders
  • Neuromuscular disease
  • Spirometry Pattern:

  • ↓ FEV1
  • ↓ FVC (more than FEV1)
  • Normal or ↑ FEV1/FVC ratio (>80%)
  • ↓ TLC
  • Key Distinction:

  • FEV1/FVC < 0.7 = Obstructive
  • FEV1/FVC normal/high + ↓TLC = Restrictive
  • Clinical Correlation

    A 65-year-old smoker with barrel chest and prolonged expiration has obstructive disease (COPD). A construction worker with progressive dyspnea and ground-glass opacities on CT likely has restrictive disease (asbestosis, silicosis).

    Memory Trick

    "Obstructive = can't get air OUT (like blowing through a straw). Restrictive = can't get air IN (like breathing with a tight corset)."